《生命科学》 2025, 37(8): 1020-1030

人造细胞在生物医学领域的应用

许文霞 , 张祥祥 , 李书彬 , 韩晓军^*

哈尔滨工业大学化工与化学学院，城乡水资源与水环境全国重点实验室，新能源转化与存储关键材 料工业和信息化部重点实验室，黑龙江省分子科学联合实验室(国际合作)，哈尔滨 150001

摘　要：

人造细胞具有结构简单、参数可控以及生物相容性良好等优势，在生物医学领域展现出广泛的应用前景。当前，人造细胞主要作为药物递送系统在疾病治疗中发挥作用。本文总结了人造细胞在内分泌系统疾病( 糖尿病及高尿酸血症)、循环系统疾病( 高血压及冠心病) 以及免疫系统疾病( 感染性疾病及癌症)等治疗中的研究现状，并对其目前存在的问题以及未来的发展方向进行了展望。

通讯作者：韩晓军 , Email:hanxiaojun@hit.edu.cn

The application of artificial cells in biomedical fields

XU Wen-Xia , ZHANG Xiang-Xiang , LI Shu-Bin , HAN Xiao-Jun^*

State Key Laboratory of Urban-rural Water Resource and Environment, MIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage, Heilongjiang Provincial Joint Laboratory of Molecular Science (International Cooperation), School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150001, China

Abstract:

Artificial cells have the advantages of simple structure, controllable parameters, and good biocompatibility, showing a broad application prospect in the biomedical field. Currently, artificial cells mainly play a role as a drug delivery system in the treatment of diseases. This paper summarizes the research status of artificial cells in the treatment of endocrine system diseases (diabetes and hyperuricemia), circulatory system diseases (hypertension and coronary heart disease), and immune system diseases (infectious diseases and cancer). At the end, this paper proposes challenges and future development directions.

Communication Author：HAN Xiao-Jun , Email:hanxiaojun@hit.edu.cn