《生命科学》 2025, 37(5): 558-566

水稻抗稻瘟病基因克隆及其育种应用研究进展

肖　宁^1,2 , 吴云雨^1,2 , 王如意³ , 赵均良⁴ , 余　玲^1,2 , 高　鹏^1,2 , 郝泽芸³ , 宁约瑟^3,* , 李爱宏^1,2,*

¹江苏里下河地区农业科学研究所/国家水稻产业技术体系扬州试验综合站，扬州 225007 ²生物育种钟山实 验室，南京 210014 ³中国农业科学院植物保护研究所/植物病虫害综合治理全国重点实验，北京 100193 ⁴广东省农业科学院水稻研究所/广东省水稻科学技术重点实验室/广东省水稻工程实验室，广州 510640

摘　要：

水稻是我国的主要粮食作物，由稻瘟菌侵染引起的稻瘟病是危及粮食安全的主要病害之一。长期的应用实践表明，利用抗性基因培育抗病品种是防控稻瘟病最经济、有效和环保的途径。本文概述了稻瘟病抗病基因克隆进展，综述了近期稻瘟病抗病基因育种进展以及面临的主要问题与挑战，提出加大种质资源稻瘟病抗性鉴定和创新智能设计育种新策略等下阶段重点研究方向。

通讯作者：宁约瑟 , Email:ningyuese@caas.cn 李爱宏 , Email:yzlah@126.com

Advancements in cloning of rice blast resistance genes and their application in breeding

XIAO Ning^1,2 , WU Yun-Yu^1,2 , WANG Ru-Yi³ , ZHAO Jun-Liang⁴ , YU Ling^1,2 , GAO Peng^1,2 , HAO Ze-Yun³ , NING Yue-Se^3,* , LI Ai-Hong^1,2,*

¹Lixiahe Region Agricultural Research Institute of Jiangsu Province, Yangzhou Comprehensive Test Station of System of Industrial Technology in Rice, Yangzhou 225007, China ²Zhongshan Biological Breeding Laboratory, Nanjing 210014, China ³State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, China ⁴Rice Research Institute of Guangdong Academy of Agricultural Sciences, Guangdong Key Laboratory of Rice Science and Technology, Guangdong Rice Engineering Laboratory, Guangzhou 510640, China

Abstract:

Rice is the primary staple crop in China, but its production faces significant threats from rice blast, a disease caused by the rice blast fungus. Long-term  practices have shown that cultivating resistant rice varieties by incorporating resistance genes is the most economical, effective, and environmentally friendly method to combat this disease. This paper reviews recent advancements in cloning blast resistance genes,  highlights the main challenges in breeding these genes, and suggests key research directions for the future. These directions include improving the identification of blast resistance in germplasm resources and developing innovative breeding strategies through intelligent design.

Communication Author：NING Yue-Se , Email:ningyuese@caas.cn LI Ai-Hong , Email:yzlah@126.com