《生命科学》 2018, 30(9): 1010-1018

国内外CRISPR/Cas9基因编辑专利技术发展分析

范月蕾，王慧媛，王恒哲，于建荣*

(中国科学院上海生命科学信息中心，上海 200031)

摘　要：摘　要：CRISPR/Cas9 是一种近年来备受瞩目的基因编辑工具，在医疗、农业、环境等领域呈现出广阔的应用前景。该领域的专利作为技术信息的重要载体，对于CRISPR/Cas9 基因编辑工具的情报研究具有重要的意义。现通过分析德温特创新平台DI 收录的2005—2017 年的CRISPR/Cas9 基因编辑技术相关专利，对国内外CRISPR/Cas9 基因编辑技术研究领域的专利发展情况与技术布局进行对比，以了解国内外该领域的技术发展状况。

Patent analysis on the development of domestic and foreign gene editing technologies

FAN Yue-Lei， WANG Hui-Yuan， WANG Heng-Zhe， YU Jian-Rong*

(Shanghai Information Center for Life Sciences， Chinese Academy of Sciences， Shanghai 200031， China)

Abstract: Abstract: CRISPR/Cas9 is a kind of high-profile gene editing tool， which has a broad application prospect in medical treatment， agriculture， environment and so on. As an important carrier of technical information， patents in this field is of great significance for intelligence research of CRISPR/Cas9. This paper analyzes domestic and foreign patents of CRISPR/Cas9 gene editing technologies during priority years 2005-2017 from Derwent Innovation (DI)， and compares the development trend and technical allocation at home and abroad in order to investigate the development status of CRISPR/Cas9 technologies.