《生命科学》 2025, 37(11): 1375-1379

从主动健康模式看《赫尔辛基宣言》最新修订版本

吴家睿^1,2,*

¹上海交通大学安泰经济与管理学院主动健康战略与发展研究院，上海 200030 ²中国科学院上海高等研究院国家蛋白质科学研究(上海)设施，上海 201210

摘　要：

世界医学会制定的《赫尔辛基宣言》是规范医学研究活动最重要的医学伦理原则。该学会于2024年10 月发布了经过重大修改的第十版，其中最主要的修改就是将研究活动中的“受试者”术语改为“参与者”。笔者认为这一重大修改与当前中国推行的“每个人是自己健康第一责任人”的主动健康新模式高度契合。据此出发，笔者从“被动受试与主动参与”、“自主个体与脆弱个体”和“个人权利与公众利益”三个方面介绍和讨论该修订版。

通讯作者：吴家睿 , Email:wujr@sibs.ac.cn

Understanding the latest revised “Declaration of Helsinki”from the view of proactive healthcare

WU Jia-Rui^1,2,*

¹Institute of Proactive Healthcare, Antai College of Economics and Management, Shanghai Jiao Tong University, Shanghai 200030, China ²National Facility for Protein Science in Shanghai, Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai 201210, China

Abstract:

The Declaration of Helsinki, formulated by the World Medical Association, is the most important medical ethical principle regulating medical research activities. In October 2024, the association released a significantly revised tenth edition, with the most notable change being the replacement of the term “subject” in research activities with “participant”. This major revision is highly consistent with the new proactive healthcare model currently promoted in China, which  emphasizes that “everyone is the first responsible person for their own health”. Based on this, the author introduces and discusses the revised version from three aspects: “passive subject and active participant”, “autonomous individual and vulnerable individual”, and “individual rights and public interests”.

Communication Author：WU Jia-Rui , Email:wujr@sibs.ac.cn