《生命科学》 2025, 37(6): 625-634

植物特异性HD-Zip转录因子在生长发育与逆境响应中的功能研究进展

张　薇 , 赵礼轲 , 张丙林 , 刘卫娟^* , 邹华文^*

长江大学农学院，荆州 434025

摘　要：

HD-Zip 是植物所特有的转录因子，其结构包含一个保守的同源结构域(HD)，以及一个负责蛋白质二聚化的保守亮氨酸拉链基序(LZ)，所以被命名为同源结构域亮氨酸拉链(HD-Zip)。根据它们的序列同源性、DNA 结合特异性和生理功能，HD-Zip 蛋白家族可分为4 个亚家族：HD-Zip I、HD-Zip II、HD-Zip III 和HD-Zip IV。研究表明HD-Zip 家族基因广泛参与植物生长发育及对各种生物( 病害、虫害) 和非生物( 干旱、高盐、高温等) 逆境胁迫的响应过程。本文综述了HD-Zip 转录因子的结构、分类及生物学功能，并对今后的研究重点进行展望。

通讯作者：刘卫娟 , Email:wjliu@yangtzeu.edu.cn 邹华文 , Email:zouhuawen@yangtzeu.edu.cn

Research advances in the roles of plant-specific HD-Zip transcription factors in growth, development, and stress response

ZHANG Wei , ZHAO Li-Ke , ZHANG Bin-Lin , LIU Wei-Juan^* , ZOU Hua-Wen^*

College of Agriculture, Yangtze University, Jingzhou 434025, China

Abstract:

HD-Zip is a transcription factor unique to plants, which contains a conserved homologous domain (HD) and a conserved leucine zipper motif (LZ) responsible for protein dimerization. Therefore, it is named homologous domain leucine zipper (HD-Zip). According to their sequence homology, DNA binding specificity and physiological functions, the HD-Zip protein family can be divided into four subfamilies, HD-Zip I, HD-Zip II, HD-Zip III and HD-Zip IV. Studies have shown that HD-Zip family genes are widely involved in plant growth and development, as well as responses to various biotic (diseases, pests) and abiotic (drought, high salt, high temperature, etc.) stresses. This article reviews the structure, classification and biological functions of HD-Zip transcription factors, and then raises some prospects for future research.

Communication Author：LIU Wei-Juan , Email:wjliu@yangtzeu.edu.cn ZOU Hua-Wen , Email:zouhuawen@yangtzeu.edu.cn