《生命科学》 2023, 35(4): 480-485

睾丸巨噬细胞的研究进展

李斯特 , 唐玉玲 , 张依量 , 王　进 , 武文卿 , 邱业峰^*

军事科学院军事医学研究院实验动物中心，北京 100071

摘　要：

睾丸作为重要的男性生殖器官，具有复杂的生殖- 内分泌- 免疫调控网路。睾丸巨噬细胞在血管形成、精子发生、类固醇激素生成、免疫抑制和细菌病毒感染等方面有着非常重要的作用。本文通过综述睾丸巨噬细胞的定位、分类、发育来源以及功能等来说明其在睾丸中的地位及意义，以期为研究睾丸巨噬细胞的功能和治疗男性不育症、睾丸炎症等提供理论依据。

通讯作者：邱业峰 , Email:qiuyefeng2001@163.com

Research progress of testicular macrophages

LI Si-Te , TANG Yu-Ling , ZHANG Yi-Liang , WANG Jin , WU Wen-Qing , QIU Ye-Feng^*

Laboratory Animal Center, Academy of Military Medical Sciences, Academy of Military Science, Beijing 100071, China

Abstract:

As an important male reproductive organ, testis has a complex reproductive endocrine immune regulatory network. Testicular macrophages play an important role in angiogenesis, spermatogenesis, testosterone production, immunosuppression, and bacterial/viral infection. In this review, we discuss the location, classification, developmental sources, and functions of testicular macrophages to explain their status and significance in testis, providing a theoretical basis for the study of the function of testicular macrophages and the treatment of male infertility and orchitis.

Communication Author：QIU Ye-Feng , Email:qiuyefeng2001@163.com