《生命科学》 2023, 35(1): 63-71

2022年合成生物学发展态势

刘　晓¹ , 张学博¹ , 陈大明¹ , 汪　哲^1,2 , 熊　燕^1,*

¹中国科学院上海营养与健康研究所，中国科学院上海生命科学信息中心，上海 200031 ²中国科学院大学，北京 100049

摘　要：

合成生物学已经进入快速发展阶段，突破性成果不断涌现，技术转化与产业应用也初见成效。DNA 合成、基因编辑、计算机辅助设计和过程自动化、机器学习等技术的进步和相关平台的建设，以及政策的支持和投融资的持续活跃，有望进一步推动生物产业及生物经济的发展。在新一轮科技变革与保护自然环境、减少碳排放的背景下，世界主要国家更加注重生物经济的可持续发展。该文系统梳理了全球合成生物学在2022 年的战略规划、研发和产业等方面的进展，展望了未来在技术创新、产业应用等方面的发展前景。

通讯作者：熊　燕 , Email:yxiong@sinh.ac.cn

Development trend of synthetic biology in 2022

LIU Xiao¹ , ZHANG Xue-Bo¹ , CHEN Da-Ming¹ , WANG Zhe^1,2 , XIONG Yan^1,*

¹Shanghai Information Center for Life Sciences, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai 200031, China ²University of Chinese Academy of Sciences, Beijing 100049, China

Abstract:

Synthetic biology has entered a stage of rapid development, breakthroughs are constantly emerging, and technology transformation and industrial applications have also achieved initial results. Advances in technologies such as DNA synthesis, gene editing, computer-aided design, process automation, machine learning and the construction of related platforms, as well as the continuous active investment and financing, are expected to further promote the development of the bioindustry and bioeconomy. Under the international background of a new round of scientific and technological change, protection of the natural environment, and reduction of carbon emissions, major countries in the world are paying more attention to the sustainable development of the bioeconomy. This article systematically reviews the national strategic planning, R&D and industry of synthetic biology in 2022, and forward to the future development in technological innovation and industrial implementation.

Communication Author：XIONG Yan , Email:yxiong@sinh.ac.cn