《生命科学》 2021, 33(12): 1469-1475

DNA信息存储的机遇与挑战

强　薇¹ , 沈　玥² , 戴俊彪^1,*

¹中国科学院深圳先进技术研究院，深圳合成生物学创新研究院，广东省合成基因组学重点实验室，深圳市合成基因组学 重点实验室，深圳 518055 ²深圳华大生命科学研究院，广东省高通量基因组测序与合成编辑应用实验室，深圳 518083

摘　要：

在高度信息化的现代社会中，现有的硅基存储资源将难以满足爆炸式增长的信息总量。基于DNA介质的信息存储融合了多个学科领域，提供了一种新的存储模式，并在世界范围内取得了相当的进展。该文首先对目前DNA 信息存储所取得的进展进行梳理归纳，继而总结了DNA 信息领域现阶段所面临的关键问题，最后对DNA 信息存储领域未来进行展望，以期为下一步研究提供方向。

通讯作者：戴俊彪 , Email:junbiao.dai@siat.ac.cn

The opportunities and challenges in DNA digital data storage

QIANG Wei¹ , SHEN Yue² , DAI Jun-Biao^1,*

¹Guangdong Provincial Key Laboratory of Synthetic Genomics and Shenzhen Key Laboratory of Synthetic Genomics, Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China ²Guangdong Provincial Key Laboratory of Genome Read and Write, BGI-Shenzhen, Shenzhen, 518083, China

Abstract:

In modern society, the amount of information is exploding. However, current silicon-based storage is limited by the availability of the materials and quickly behinds the needs. Storing information in DNA is an interdisciplinary filed, which has the potential to provide a solution for the increased information. The filed has made many achievements in the past decade. Here, we start the review by briefly introducing the progress of the field and highlighting a few recent achievements. Next, we focus our attention on bottlenecks which are currently limiting the application of DNA data storage and discuss potential solutions. Finally, future directions are proposed.

Communication Author：DAI Jun-Biao , Email:junbiao.dai@siat.ac.cn