《生命科学》 2017, 29(1): 1-7
摘 要：摘 要：生殖健康事关人口健康。在育龄女性卵巢中，原始卵泡的形成、始动募集和周期性募集等生理过程不仅是其生育能力的长短和质量的决定因素，也是诱发卵巢功能障碍、不孕不育和卵巢疾病的几个主要环节。遗憾的是，目前尚未充分认识其生理机制，而近年来的调查显示，我国生殖健康状况不容乐观。因此，拟通过对现阶段相关基础研究的剖析，探讨加强卵巢功能调控研究，尤其是促进卵泡发育和周期性募集的细胞与分子调控机理研究的必要性。结合自己的研究，对今后的研究方向提出了一些建议，希望能为促进我国生殖领域基础研究起到抛砖引玉的作用。
Abstract: Abstract: Reproductive health is related to the health of the population. In the ovaries of women at childbearing age， the formation of primordial follicles， initiating the recruitment and periodic recruitment and other physiological processes not only determine the length and quality of the fertility， but are also the pivotal points that may induce ovarian dysfunction， infertility and ovarian diseases. Unfortunately， we have not yet fully understood the physiological mechanism of reproduction so far. Recent investigation shows that the general reproductive health status is not optimistic in China. Therefore， in this paper， based on the analysis of the current basic researches of reproduction， the authors present their opinions on strengthening the studies upon the regulation of ovarian function， especially the necessity of promoting the study of cellular and molecular level of follicular development as well as periodic recruitment regulation mechanism. Based on our own researches， some suggestions for the future researches are given. We hope that our suggestions may be helpful to promote the reproductive basic research in China.
