《生命科学》 2015, 27(11): 1320-1327

蓝绿菌生物钟调控动力学和机制研究进展

李丛鑫，王鹏业，王渭池*

(中国科学院物理研究所北京凝聚态物理国家实验室-软物质物理重点实验室，北京 100190)

摘　要：摘　要：生物钟的振荡过程是生命体中典型的非线性动力学现象，它们对细胞基因表达、信号转导以及细胞的新陈代谢等过程起重要的调控作用。通过对生物钟振荡过程各个调控单元或模块之间动力学和调控机制的定量分析，有助于更深入、更直观地了解生物钟在时间尺度和空间尺度上如何精确地调控生物体的生命过程。

Regulatory mechanism and dynamics of cyanobacterial circadian clock

LI Cong-Xin， WANG Peng-Ye， WANG Wei-Chi*

(Key Laboratory of Soft Matter Physics， Beijing National Laboratory for Condensed Matter Physics，Institute of Physics， Chinese Academy of Sciences， Beijing 100190， China)

Abstract: Abstract: Circadian oscillation is a typical nonlinear behaviour in nature. A sustained oscillatory rhythm is fundamental for gene expression， signal transduction and metabolism in living cells. By quantifying the interactions among the elements (or modules) of biological clocks， it is certainly helpful for us to understand how precisely the circadian clocks regulate the life processes in spatiotemporal context.