《生命科学》 2015, 27(9): 1114-1119

树鼩在神经系统疾病中的应用研究进展

林　娜，陈梅容，王廷华*

(昆明医科大学神经科学研究所，昆明 650031)

摘　要：摘　要：近年来研究表明，树鼩的生理、生化和解剖学等许多生物学特性比啮齿类更接近于人类。因此，关于树鼩的研究越来越广泛，涉及病毒、内分泌和肿瘤等方面。此外，树鼩是神经系统高度发达的动物，与啮齿类相比存在其特有的优势。概述了国内、外树鼩在脑血管病、抑郁症和阿尔兹海默病中的研究现状，以及CRISPR/Cas 系统在树鼩中的运用前景，期望可以对今后的基础研究和临床研究提供导向作用。

Advances of tree shrews in the nervous system diseases

LIN Na， CHEN Mei-Rong， WANG Ting-Hua*

(Institute of Neuroscience， Kunming Medical University， Kunming 650031， China)

Abstract: Abstract: Studies have shown that many biological characteristics including physiology， biochemistry and anatomy of tree shrews are closer to humans than rodents. So， there are more and more researches on tree shrews， such as virus， endocrine， tumors and so on. In addition， the nervous system of tree shrews is highly developed， and shows the unique advantages compared to rodents. In this review， we summarized the researches at home and abroad on cerebrovascular disease， depression， Alzheimer’s disease and introduced the application of the CRISPR/Cas system in tree shrews to offer guide for basic research and clinical studies in the future.