从DNA合成技术角度阐述合成生物学
田敬东1,2
(1 中国科学院天津工业生物技术研究所,天津 300308;2 美国杜克大学生物医学工程系,基因组科学与政策研究所,北卡罗来纳州 27708)

摘 要:摘 要:合成生物学是一个拥有巨大潜力的新兴学科,合成生物学技术的发展将会对未来生物、医药、农业、能源、材料和环保等方面产生巨大的推进作用。基因合成是合成生物学中最基本和使用最多的一种技术手段,合成生物学的快速发展对基因合成能力提出了空前需求。综述基因合成技术的发展历史、现状和未来趋势,探讨基因合成技术在合成生物学以及整个生命科学研究中的应用和重要意义。
关键词:DNA合成;基因合成;基因组合成;基因芯片;合成生物学

Gene synthesis technology and synthetic biology
TIAN Jing-Dong1,2
(1 Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, China;2 Department of Biomedical Engineering, Institute for Genome Sciences and Technology, Duke University, NC 27708, USA)

Abstract: Abstract: Synthetic biology is an emerging field with great potentials in promoting future developments in biomedical research, agriculture, bioenergy, biomaterial and bioremediation. Gene synthesis is the most basic and most wildly used technique in synthetic biology. The rapid development of this field is creating insatiable demand for gene synthesis. This paper will review the history, current status and future trend of gene synthesis and discuss its applications and significance in synthetic biology as well as the life science research as a whole.
Key words: DNA synthesis; gene synthesis; genome synthesis; microarray; synthetic biology

Back to top