《生命科学》 2009, 21(1): 131-134

葛根素对中枢神经系统神经细胞保护作用的研究进展

刘本娟，曹宝萍，吴民耀*

陕西师范大学生命科学学院，西安 710062

摘　要：摘　要：葛根素(puerarin)是从中药葛根中提取的主要有效成分之一，为一种异黄酮化合物。它具有抑制脑细胞凋亡，保护神经细胞的能力，还能够提高神经元抵抗损伤的能力，可用于治疗脑损伤以及神经退行性疾病。本文就葛根素对中枢神经系统神经细胞的保护作用及机制方面的研究进展做一综述。
关键词：葛根素；神经细胞；保护作用

Progress in the research on neuroprotective effects of puerarin in the central nervous system

LIU Ben-juan， CAO Bao-ping， WU Min-yao*

College of Life Science， Shanxi Normal University， Xi{$39}an 710062， China

Abstract: Abstract: Puerarin is one of the major isoflavonoid compounds isolated from Radix Puerariae， which has been used in traditional Chinese medicine for centuries. The compound was found to inhibit neuronal apoptosis， protect nerve  cells against hypoxic/ischemic injuries. Thus， puerarin may be used to treat brain traumas and neurodegenerative diseases. This article reviews the recent progress in research on neuroprotective effects of puerarin and the related mechanisms.
Key words: puerarin; neural cells; protective effect