《生命科学》 2008, 20(4):

线粒体融合蛋白Mitofusin在胰岛素抵抗发生与防治中的作用

漆正堂1,2,丁树哲2*,贺　杰1

（1衡阳师范学院体育系，衡阳421008; 2华东师范大学体育与健康学院，上海200241）

摘　要：摘  要: Mitofusin是线粒体融合的关键介导蛋白，与胰岛素抵抗及2型糖尿病的发生与防治密切相关。本文就Mitofusin在胰岛素抵抗发生与运动防治中的作用作一综述。
关键词：Mitofusin；线粒体融合；胰岛素抵抗
中图分类号：Q44；Q244    文献标识码：A

Roles of Mitofusin on the pathogenesis, prevention and cure of insulin resistance

QI Zheng-tang1,2,DING Shu-zhe2*,HE Jie1

(1 Department of Physical Education, Hengyang Normal University, Hengyang 421008, China;2 College of Physical Education and Health, East China Normal University, Shanghai 200241, China)

Abstract: Abstract: Mitofusin was a key regulator of mitochondrial fusion and closely related to insulin resistance and type 2 diabetes.  Roles of Mitofusin on the pathogenesis, prevention and cure of insulin resistance were summarized in the review.
Key words: Mitofusin；mitochondrial fusion；insulin resistance