《生命科学》 2008, 20(2):

螺旋藻藻蓝蛋白光敏作用的研究进展

范 敏1，王雪青1*，段开红2，庞广昌1

(1天津市食品与生物技术重点实验室，天津商业大学生物技术与食品科学学院，天津 300134；2内蒙古农业大学生物工程学院，呼和浩特 010018)

摘　要：摘　要：螺旋藻是一种广泛养殖的丝状体蓝藻。从螺旋藻中提取的藻蓝蛋白具有抗肿瘤和增强免疫等多种生物学功能，作为光敏剂，藻蓝蛋白可应用于肿瘤治疗。本文阐述了藻蓝蛋白的结构、光动力疗法的原理和藻蓝蛋白光敏作用的研究进展，并介绍了藻蓝蛋白在光动力疗法中的应用现状与前景。
关键词：螺旋藻；藻蓝蛋白；光动力疗法；光敏剂
中图分类号：Q949.225; Q946.1　　文献标识码：A

Progress of the studies on photosensitization from Spirulina phycocyanin

FAN Min1, WANG Xue-qing1*, DUAN Kai-hong2, PANG Guang-chang1

(1 Tianjin Key Laboratory of Food Biotechnology, College of Biotechnology and Food Science, Tianjin University of Commerce , Tianjin 300134, China; 2 College of Bioengineering, Inner Mongolia Agricultural University, Huhhot 010018, China)

Abstract: Abstract: Phycocyanin extracted from Spirulina possesses many kinds of biological functions including the effects of antitumor and enhancing the immunity, etc. The phycocyanin may be used as a prosperous photosensitizer and possibly applied to the photodynamic therapy of cancers. The structure, photosensitization of phycocyanin and the principles of photodynamic therapy were mainly reviewed. And the application status and prospects of the photodynamic therapy of the phycocyanin are introduced.
Key words:  Spirulina; phycocyanin; photodynamic therapy; photosensitizer