摘 要:
摘 要:乳腺癌是发生在乳房腺上皮组织的恶性肿瘤,其发病率占女性恶性肿瘤首位。近年来,蛋白质组研究广泛深入乳腺癌发病机理、临床早期诊断和治疗等各个方面。本文比较系统地综述了乳腺蛋白质组研究的样品处理、研究技术和研究成果。
关键词:乳腺癌;蛋白质组;激光捕获显微切割(LCM);质谱
中图分类号:Q51;R737.9 文献标识码:A
Abstract: Abstract: Breast cancer is a malignant cancer that is developed in breast epithelial tissue. The mortality of breast cancer is at the first place in female malignant cancers. In recent years, proteome research is widely used in pathogenesis, clinical early diagnosis and treatment of breast cancer. In this review, we systematically summarized the progress of proteome research in sample treatment, experiment technology and research achievements of breast cancer.
Key words: breast cancer; proteomics; laser capture microdissection(LCM); mass spectrometry