《生命科学》 2025, 37(2): 170-185

补充植物提取物预防运动诱导的肌肉损伤的研究进展

许亚民¹ , 许嘉兴² , 王　政^2,*

¹山西工商学院，太原 030072 ²齐鲁理工学院，济南 250200

摘　要：

随着健康中国战略的实施，越来越多的人加入体育运动中，不适当的运动易引起损伤。其中，运动性肌肉损伤(exercise-induced muscle damage, EIMD) 是由于长时间或高强度的运动，导致肌肉收缩能力受损、出现氧化应激及炎症反应，从而不同程度地影响人们的日常生活。植物提取物因具有抗氧化、抗炎等生物学功能，成为预防EIMD 的极佳选择。本文通过归纳总结补充植物提取物预防EIMD 的现有机制及临床研究，发现植物提取物可以通过降低肌肉损伤标志物水平、提高抗氧化酶活性、抑制氧化应激和炎症等缓解EIMD，且富含多酚和中药皂苷等活性化合物的植物提取物已被众多临床研究证明可以有效减轻EIMD并加速肌肉功能恢复。总之，补充植物提取物是预防EIMD 的重要选择。

通讯作者：王　政 , Email:wxz298499@163.com

Research progress on supplementing plant extracts to prevent exercise induced muscle injury

XU Ya-Min¹ , XU Jia-Xing² , WANG Zheng^2,*

¹Shanxi Technology and Business University, Taiyuan 030072, China ²Qilu Institute of Technology, Jinan 250200, China

Abstract:

With the implementation of the Healthy China Strategy, more and more people are participating in sports, inappropriate sports are prone to cause injuries, among which exercise-induced muscle damage (EIMD) is due to prolonged or high-intensity exercise, which leads to impairment of muscle contraction, oxidative stress and inflammatory response, thus affecting people's daily lives to varying degrees. Plant extracts are an excellent choice for the prevention of EIMD due to their biological functions such as antioxidant and anti-inflammatory. In this paper, we summarize the existing mechanisms and clinical studies on the prevention of EIMD by supplementation with plant extracts, and find that plant extracts can alleviate EIMD by reducing the levels of muscle damage markers, increasing the activity of antioxidant enzymes, and inhibiting oxidative stress and inflammation, etc. In addition, plant extracts rich in polyphenol and Chinese herbal saponin have been shown to be effective in alleviating EIMD and accelerating recovery of muscle function in a number of clinical studies. In conclusion, supplementation with plant extracts is an important option for the prevention of EIMD.

Communication Author：WANG Zheng , Email:wxz298499@163.com