《生命科学》 2024, 36(11): 1420-1427

糖尿病诊断及治疗策略探讨

陈子怡¹ , 谭文芝¹ , 郑金海² , 吴　昊¹ , 文　李^1,*

¹长沙理工大学食品与生物工程学院，长沙410114 ²湖南大学生命医学交叉研究院，长沙410114

摘　要：

糖尿病作为一种常见的慢性代谢疾病，已经成为全球公共卫生问题不可忽视的重要组成部分。深入了解糖尿病的诊断以及治疗方法尤为重要。现有的糖尿病治疗方法已经取得了一定的成果，但仍面临着一系列挑战。新型的治疗方法包括但不限于新的血糖靶点利用、β 细胞替代疗法及口服肽类药物等。本文综述了糖尿病的诊断和治疗方法，并展望基因工程菌作为糖尿病药物载体的潜力，为研究和开发糖尿病药物提供理论依据和启示。

通讯作者：文　李 , Email:wl@csust.edu.cn

Review on diabetes diagnosis and treatment strategies

CHEN Zi-Yi¹ , TAN Wen-Zhi¹ , ZHENG Jin-Hai² , WU Hao¹ , WEN Li^1,*

¹School of Food Science and Bioengineering, Changsha University of Science and Technology, Changsha 410114, China ²School of Biomedical Sciences, Hunan University, Changsha 410114, China

Abstract:

As a common chronic metabolic disorder, diabetes has become an important part of the global public health problem that cannot be ignored. It is important to have a better understanding of diabetes’s diagnosis and treatment. Existing diabetes treatments have obtained some achievements, but there are still a number of challenges. Novel therapeutics include, but are not limited to, the utilization of new blood glucose targets, β cell replacement therapy, and oral peptides. This article summarizes the diagnosis and treatment of diabetes mellitus, and forecasts the use of genetically engineered bacteria as the potential carriers of diabetes drugs, which can provide theoretical basis and enlightenment for the development of diabetes treatments.

Communication Author：WEN Li , Email:wl@csust.edu.cn