《生命科学》 2024, 36(3): 381-387

皮肤瘙痒的成因及其与昼夜节律关系的研究进展

何　乔¹ , 李　丽¹ , 高文红² , 凌　霄³ , 郭苗苗^1,*

¹北京工商大学轻工科学与工程学院，北京 100048 ²润芳可(上海)生物科技 有限公司，上海 201499 ³北京尚捷优蓝科技有限公司，北京 100872

摘　要：

瘙痒是皮肤常见的症状，包括由系统性基础疾病引起的全身性瘙痒，和皮肤疾病或外部条件导致的局部皮肤瘙痒。本文简要阐述了系统性基础疾病导致的全身性瘙痒以及皮肤疾病引起的局部皮肤瘙痒，并对不良生活条件( 如空气污染、熬夜及不健康饮食) 导致的皮肤局部瘙痒，及进而引起的昼夜节律紊乱进行总结分析，并从调节昼夜节律角度讨论缓解皮肤瘙痒的方法。

通讯作者：郭苗苗 , Email:guomiaomiao7@163.com

Research progress in the cause of skin itching and its circadian rhythm

HE Qiao¹ , LI Li¹ , GAO Wen-Hong² , LING Xiao³ , GUO Miao-Miao^1,*

¹School of Light Industry Science and Engineering, Beijing Technology and Business University, Beijing 100048, China ²Revacl (Shanghai) Biotechnology Co., Ltd., Shanghai 201499, China ³Beijing Lan Divine Technology Co., Ltd., Beijing 100872, China

Abstract:

Pruritus is a common symptom of the skin, including the systemic itching resulted from systemic
underlying diseases and the skin partial itching caused by primary skin disorders or external conditions. In this article, we briefly expound itching caused by systemic underlying diseases and primary skin disorders, and summarize the partial itching of skin caused by undesirable living conditions (such as air pollution, staying up late and unhealthy diet) and the resulted circadian rhythm disorders. We discuss how to relieve skin itching from the perspective of regulating circadian rhythm.

Communication Author：GUO Miao-Miao , Email:guomiaomiao7@163.com