《生命科学》 2022, 34(10): 1317-1326

基因编辑技术监管现状研究

张丽雯¹ , 刘加兰² , 王　洪^1,3 , 于建荣^1,*

¹中国科学院上海营养与健康研究所，中国科学院上海生命科学信息中心，上海 200031 ²中国科学院昆明动物研究所，昆明 650201 ³中国科学院大学，北京 100049

摘　要：

基因编辑因其“精确性、易用性、低成本”的技术优势掀起了全世界的研究热潮。尤其是2013年CRISPR 技术的诞生，带动基因编辑飞速发展，已广泛应用于医学、农业、工业、环境等领域，也引发了一系列关于安全及伦理风险的讨论，其中“自上而下”的监管将发挥重要作用。本文概述了近年来基因编辑技术的应用进展和问题探讨，从人类、植物、动物基因编辑三方面出发，重点梳理了国际及我国的基因编辑监管现状，并对我国的基因编辑监管提供咨询参考建议。

通讯作者：于建荣 , Email:jryu@sinh.ac.cn

Current supervision status of gene editing technology

ZHANG Li-Wen¹ , LIU Jia-Lan² , WANG Hong^1,3 , YU Jian-Rong^1,*

¹Shanghai Information Center for Life Sciences, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai 200031, China ²Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650201, China ³University of Chinese Academy of Sciences, Beijing 100049, China

Abstract:

Gene editing has aroused a worldwide research upsurge for the advantages of accuracy, usability, and low cost. The birth of CRISPR technology in 2013 drove the rapid development of gene editing, which has been widely used in medicine, agriculture, industry, environment and so on, and also triggered a series of discussions on safety and ethical risks. “Top-down” supervision plays an important role. Focusing on human, plant and animal gene editing, in this paper we summarize the application progress and problem discussion of gene editing technology, comb the current situation of gene editing supervision in China and abroad, and propose some suggestions on supervision.

Communication Author：YU Jian-Rong , Email:jryu@sinh.ac.cn