《生命科学》 2021, 33(5): 565-575

GATA基因家族在无脊椎动物中的研究进展

张婷婷 , 秦贞奎 , 刘丹雯 , 马玉彬^*

中国海洋大学海洋生物遗传学与育种教育部重点实验室，青岛 266003

摘　要：

GATA 基因家族是一类含有锌指结构域的转录因子，因特异性地结合共同的核苷酸序列A/T(GATA)A/G 而得名。该家族在动物界广泛分布，其功能主要涉及胚层分化、器官发育和功能维持等方面。现对GATA 家族的基本信息、结构和分类进行简介，梳理近年来GATA 家族成员在无脊椎动物中的研究进展，并对未来的研究方向进行展望。

通讯作者：马玉彬 , Email:mayubin@ouc.edu.cn

Advances in GATA gene family of invertebrate

ZHANG Ting-Ting , QIN Zhen-Kui , LIU Dan-Wen , MA Yu-Bin^*

Key Laboratory of Marine Genetics and Breeding, Ministry of Education, Ocean University of China, Qingdao 266003, China

Abstract:

The GATA family are transcription factors containing one or two zinc-finger DNA-binding domains. They are so-called because they bind to the consensus DNA sequence A/T(GATA)A/G. They have been found throughout the animal kingdom, and have been shown to play critical roles in germ layer differentiation, organ development and function maintenance. This article briefly introduces the basic information, structure and classification of the GATA family, summarizes the recent research progress of GATA family members in invertebrate, and finally looks forward to the future research directions.

Communication Author：MA Yu-Bin , Email:mayubin@ouc.edu.cn