《生命科学》 2020, 32(8): 791-797

miRNA在调控奶畜乳脂代谢中的作用研究进展

许浩天¹ , 连　帅^1,2 , 王建发^1,2,* , 武　瑞^1,2

¹黑龙江八一农垦大学动物科技学院，大庆 163319 ²黑龙江省牛病防制重点实验室，大庆 163319

摘　要：

乳汁中乳脂率是决定乳品质高低的主要因素之一。MicroRNA (miRNA) 是一类对基因表达起负调控作用的，长度为18~25 个核苷酸的非编码RNA 分子。该文综述了乳腺组织中与乳脂代谢密切相关的miRNA 的研究进展，旨在为从表观遗传学水平上探索哺乳动物乳脂代谢新机制提供参考。

通讯作者：王建发 , Email:wjflw@sina.com

Research progress on the role of miRNA in regulating milk fat metabolism of dairy animals

XU Hao-Tian¹ , LIAN Shuai^1,2 , WANG Jian-Fa^1,2,* , WU Rui^1,2

¹College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing 163319, China ²Heilongjiang Provincial Key Laboratory of Prevention and Control of Bovine Diseases, Daqing 163319, China

Abstract:

Milk fat ratio is one of the main factors that determine the quality of milk. MicroRNA (miRNA) is a group of non-coding RNA molecules with a length of 18-25 nucleotides that negatively regulates gene expression. This paper reviewed the research progress on miRNAs that are closely related to milk fat metabolism in breast tissue to provide a reference for the exploration of the new mechanism of milk fat metabolism in mammals at the epigenetic level.

Communication Author：WANG Jian-Fa , Email:wjflw@sina.com