《生命科学》 2019, 31(11): 1099-1105
摘 要:摘 要:基底神经节是大脑皮质下一群神经核团的统称,主要负责运动调控、运动学习和情绪认识。经典的基底神经节模型描述了信息如何通过基底神经节两条神经通路返回大脑皮层,以实现对运动的正常调控。目前认为多种运动功能障碍性疾病的发生都与基底神经节功能异常有关,然而,其如何调控运动的运动学,如速度、方向和运动强度等还不是很清楚。现对基底神经节在运动调控作用中的研究进展进行综述,为进一步研究提供参考。
Abstract: Abstract: The basal ganglia is a group of subcortical nuclei responsible primarily for motor control, motor learning and emotional cognition. The classical basal ganglia model shows how information flows through the basal ganglia back to the cortex through two pathways for the proper execution of movement. Now it is considered that the occurrence of multiple dyskinesia diseases are considered related to the abnormal basal ganglia,however, it
remains unclear how they account for control in kinematics of movement such as speed, orientation or motor intensity. Accordingly, in this paper, we summarize the research process of the functions of basal ganglia in motor control, which can provide a reference for further study.