《生命科学》 2019, 31(6): 609-619

章鱼胺对昆虫性信息素感受、生殖行为和精卵排放的调控

熊佳新1，姜宏健1，嵇保中1*，刘曙雯2，王　怡1

(1 南京林业大学林学院，南方现代林业协同创新中心，南京 210037；2 南京中山陵园管理局，南京 210014)

摘　要：摘　要：章鱼胺在昆虫生殖活动中发挥重要的调控作用。章鱼胺可以降低昆虫对性信息素感受的反应阈值，提高感受的敏感性。章鱼胺与输卵管上皮细胞受体OAMB 和Octβ2R 结合，激活Ca2+/ 钙调蛋白依赖性蛋白激酶Ⅱ和蛋白激酶A，可促进肌肉松弛和输卵管管腔液体分泌。章鱼胺还能促进受精囊和卵巢围鞘的收缩。通过雌性生殖系统不同部位收缩与松弛的偶联，实现精卵排放和受精。此外，章鱼胺也可调控昆虫的求偶、抚育等生殖行为，可通过抑制腺苷酸环化酶的活性调节性信息素的合成和交配后效应。章鱼胺调控昆虫性信息素感受、生殖行为和精卵排放的研究虽然取得了显著进展，但相关机理和信号转导途径等仍需进一步探索。章鱼胺对昆虫生殖调控方面的研究将为查明昆虫生殖机制和杀虫剂开发提供重要理论参考。

Modulatory effects of octopamine on the sexual pheromone perception，    reproductive behaviors and liberation of sperms and eggs in insects

XIONG Jia-Xin1， JIANG Hong-Jian1， JI Bao-Zhong1*， LIU Shu-Wen2， WANG Yi1

(1 Co-Innovation Center for Sustainable Forestry in Southern China， College of Forestry， Nanjing Forestry University， Nanjing 210037， China; 2 The Administration Bureau of Dr. Sun Yat-sen’s Mausoleum， Nanjing 210014， China)

Abstract: Abstract: Octopamine (OA) plays a crucial role in the regulation of reproductive activities in insects. It can decrease the response thresholds and enhance the sensibility of olfactory to sex pheromones. By binding to OAMB and Octβ2R receptors on the oviduct epithelium， OA activates Ca2+/calmodulin-sensitive kinase II and protein kinase A， and triggers muscle relaxation and fluid secretion to the oviduct lumen. Meanwhile， it can stimulate spermathecae and ovarian sheath contractions. The contraction-relaxation coupling of different parts in female reproductive system makes it possible to ovulate， release sperms and fertilize eggs. Additionally， OA is also involved in courtship， parenting and other reproductive behaviors. For example， OA modulates the synthesis of sex
    pheromone and the post-mating responses by inhibiting adenylate cyclase activity. Although significant progress has been made in the above-mentioned studies， the mechanisms and signal transduction pathways are still need to be further explored. The studies mentioned above provide important references for researches on the reproductive mechanism and insecticide development in insects.