人类细胞图谱计划面临的挑战
吴家睿
(中国科学院上海生命科学研究院生物化学与细胞生物学研究所,上海 200031)

摘 要:摘 要:“人类细胞图谱”(Human Cell Atlas, HCA) 是生命科学领域最近兴起的国际大科学计划,其目标是要采用特定的分子标志物来确定人体的所有细胞类型。该计划的实施面临着巨大的挑战:有些挑战是技术性的,也许在未来能够解决;但是,有些挑战是理论性的,反映出研究者的想法与其研究对象的本性之间有着根本的冲突。

Challenges for Human Cell Atlas
WU Jia-Rui
(Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China)

Abstract: Abstract: “Human Cell Atlas” (HCA) has been recently initiated as an international grand research project in the area of life science, with the goal to construct a comprehensive catalog of all human cells based on their molecular biomarkers. The HCA project will face grand challenges, among which some are technical and some are theoretical.

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