《生命科学》 2017, 29(7): 630-635

肠道微生态与肿瘤研究进展

鄢和新，秦晨捷，张会禄，王红阳*

(第二军医大学东方肝胆外科医院生物信号转导研究室，国家肝癌科学中心，上海 200438)

摘　要：摘　要：肠道微生态是由数量庞大而结构复杂的肠道菌群所组成，参与了包括消化、代谢、免疫调节、能量转化、维护肠道黏膜防御功能等多种重要生理功能，因此具有极其重要的科学研究价值。就近年来肠道微生态与肿瘤的研究进展进行综述，为进一步研究肠道微生态如何对肿瘤的发生发展造成影响，研究如何应用肠道微生态制剂来辅助治疗肿瘤等提供理论指导。

Research advances in the relationship between intestinal micro-ecology and cancer

YAN He-Xin， QIN Chen-Jie， ZHANG Hui-Lu， WANG Hong-Yang*

(International Co-operation Lab on Signal Transduction， Eastern Hepatobiliary Surgery Hospital， Second Military Medical University， National Center for Liver Cancer， Shanghai 200438， China)

Abstract: Abstract: Intestinal micro-ecology is formed by large amounts of gut microbiome in complex composition. Because of its crucial physiological functions such as digestion， metabolism， immune regulation， energy conversion and protection of mucosal integrity， it has great scientific research value. This review focuses on the recent advances in the relationship between intestinal micro-ecology and cancer. We hope it will provide some theoretical guidance for further illustrating how the intestinal micro-ecology influences the development or progression of cancer and how we utilize the probiotics in cancer adjuvant therapy.