《生命科学》 2016, 28(6): 645-654

microRNA172参与植物生长发育及逆境响应的研究进展

王幼宁1，苏　超2，邹艳敏2，王利祥2，李　霞1，3*

(1 华中农业大学植物科学技术学院，武汉 430070；2 中国科学院遗传与发育生物学研究所农业资源研究中心，石家庄 050021；3 华中农业大学农业微生物学国家重点实验室，武汉 430070)

摘　要：摘　要：microRNA (miRNA) 是一类长约20~25 个核苷酸的非编码小分子RNA，通过和靶基因mRNA 上的一些特定序列结合，诱导靶基因mRNA 被剪切或抑制其翻译，从而在转录后水平调控植物的生长发育和对逆境的响应。microR172 (miR172) 是植物中一个保守的miRNA 家族，通过靶向调控AP2 和AP2-Like 基因在植物发育和环境适应中发挥着不可或缺的作用。已有的研究表明，miR172 及其靶基因不仅在植物的时序转换中是一个关键调控因子，也在花器官发育、土豆块茎形成、豆科结瘤和逆境响应等过程中发挥着重要调控作用。现将重点阐述这个明星miRNA 在植物生长发育及对环境因子应答过程中的研究进展，以期为深入解析miR172 靶基因的作用机理和分子调控网络提供参考。

Research progress of microRNA172 in plant development and stress responses

WANG You-Ning1， SU Chao2， ZOU Yan-Min2， WANG Li-Xiang2， LI Xia1， 3*

(1 College of Plant Science and Technology， Huazhong Agricultural University， Wuhan 430070， China; 2 Center for Agricultural Research Resources， Institute of Genetics and Developmental Biology， Chinese Academy of Sciences， Shijiazhuang 050021， China; 3 State Key Laboratory of Agricultural Microbiology， Huazhong Agricultural University， Wuhan 430070， China)

Abstract: Abstract: microRNAs (miRNAs) are endogenous non-coding RNAs that are 20-25 nucleotides (nt) in length， and regulate plant development and stress responses at post-transcriptional levels. MicroRNA172 (miR172) is a highly conserved miRNA family in plants that are crucial for phase transition，organ development and stress responses through repressing the APETALA2(AP2) or AP2-like genes encoding AP2/AP2-like transcription factors. Recently，miR172 has been identified as a key regulator of nodulation in legumes and tuber formation in potato. Here， we summarize the major findings on the miR172-mediated plant development and stress responses and discuss the recent progress that has improved our understanding of the growth regulation and plant response to abiotic stresses by miR172-mediated networks.