《生命科学》 2016, 28(1): 93-99
摘 要:摘 要:微小RNA (microRNA, miRNA) 是一种在进化上高度保守的内源性非编码单链小RNA。近年来研究表明,miRNA 在肿瘤发生发展、脂肪代谢、血管生成等方面扮演着重要的角色,其通过靶基因在一定程度上调控细胞的生长、发育和增殖,并且与多种疾病有着密切的联系。现从以上3 个方面对miR-27 的最新研究进展进行简要综述,以期为miR-27 的后续研究提供理论依据,丰富miRNA 的研究内涵。
Abstract: Abstract: MicroRNA (miRNA) is a highly conserved endogenous non-coding single stranded small RNA in evolution. Recent studies show that miRNA plays an important role in the development of tumor, angiogenesis, and energy metabolism, miRNA regulates cell growth, development and proliferation through targeting gene, and closely associates with many diseases. The objective of this review is to summarize the recent research progresses of miR-27 to improve the way for the further studies.