《生命科学》 2014, 26(12): 1248-1254

解码大脑的空间方位认知

马晓宇，林龙年^*

华东师范大学生命科学学院，脑功能基因组学教育部重点实验室，上海 200062

摘　要：在过去的几十年间，与大脑空间方位认知功能相关的位置细胞、网格细胞、头朝向细胞和边界细胞陆续被发现，它们共同构成了大脑内部的导航定位系统。O'Keefe 教授和Moser 夫妇这三位科学家也正是由于发现了位置细胞和网格细胞，而共同获得了2014 年的诺贝尔生理学或医学奖。

Decoding brain bases of spatial cognition

MA Xiao-Yu， LIN Long-Nian^*

Key Laboratory of Brain Functional Genomics (Ministry of Education)， School of Life Sciences，East China Normal University， Shanghai 200062，China

Abstract: In the past several decades， various spatial cells， including place cells， grid cells， head direction cells， and boundary cells have been discovered， constituting a positioning system in the brains that allows for spatial recognition and navigation. Prof. John O'Keefe， May-Britt Moser and Edvard I. Moser share the 2014 Nobel Prize in Physiology or Medicine for their discoveries of place cells and grid cells.