影响主动脉平滑肌细胞迁移的因素
范丽娟1,2,张 燕2,尹 苗1*,王长法2*
(1 山东师范大学生命科学学院,济南 250014;2 山东省农业科学院奶牛研究中心,济南 250100)

摘 要:摘 要:平滑肌细胞(vascular smooth muscle cell, VSMC) 的迁移对血管发育、动脉粥样硬化和术后再狭窄等起到关键性的作用。主要从激发VSMC 迁移的关键炎性细胞因子、细胞间相互作用的核心成员、microRNA、细胞骨架和上述各因素的迁移信号通路这几方面来综述VSMC 的迁移。

Influencing factors of vascular smooth muscle cell migration
FAN Li-Juan1,2, ZHANG Yan2, YIN Miao1*, WANG Chang-Fa2*
(1 College of Life Science, Shandong Normal University, Jinan 250014, China; 2 Dairy Cattle Research Center, Shandong Academy of Agricultural Science, Jinan 250100, China)

Abstract: Abstract: The migration of vascular smooth muscle cell (VSMC) plays a key role in vascular development, atherogenesis and restenosis. Here, we review recent progresses made toward the key inflammatory cytokines triggerring VSMC migration, key players between cell-matrix and cell-cell contacts, microRNA, cytoskeleton and signaling pathway events of each factor mediating VSMC migration, which are characteristics as influence factors of VSMC migration.

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