《生命科学》 2014, 26(7): 696-702
摘 要:摘 要:平滑肌细胞(vascular smooth muscle cell, VSMC) 的迁移对血管发育、动脉粥样硬化和术后再狭窄等起到关键性的作用。主要从激发VSMC 迁移的关键炎性细胞因子、细胞间相互作用的核心成员、microRNA、细胞骨架和上述各因素的迁移信号通路这几方面来综述VSMC 的迁移。
Abstract: Abstract: The migration of vascular smooth muscle cell (VSMC) plays a key role in vascular development, atherogenesis and restenosis. Here, we review recent progresses made toward the key inflammatory cytokines triggerring VSMC migration, key players between cell-matrix and cell-cell contacts, microRNA, cytoskeleton and signaling pathway events of each factor mediating VSMC migration, which are characteristics as influence factors of VSMC migration.