《生命科学》 2006, 18(5):

盘基网柄菌细胞分化及细胞比例的调控

王一铮，张　敏，侯连生^*

华东师范大学生命科学学院，上海200062

摘　要：摘　要：本文综述了盘基网柄菌(Dictyostelium discoideum)发育过程中调控细胞分化及细胞比例的一些信号分子，包括分化诱导因子(DIF-1、SDF-2)、糖原合成酶激酶(GSK-3)、环状亮氨酸拉链蛋白(rZIP)等，介绍了这些信号分子的功能及其作用机制。
关键词：盘基网柄菌；细胞分化；细胞比例；信号分子

Control of cellular differentiation and cell proportion in Dictyostelium discoideum

WANG Yi-Zheng, ZHANG Min, HOU Lian-Sheng^*

School of Life Sciences, East China Normal University, Shanghai 200062, China

Abstract: Abstract: This review summarises the signaling molecules that regulating cellular differentiation and cell proportion during Dictyostelium discoideum development, including differentiation- inducing factor (DIF-1, SDF-2), glycogen synthetase kinase (GSK-3), RING-leucine zipper protein (rZIP), etc. The functions and action mechanisms of these signaling molecules are introduced.
Key words: Dictyostelium discoideum; cellular differentiation; cell proportion; signaling molecule