《生命科学》 2013, 25(5): 511-517

单细胞衰老研究的模式生物——酿酒酵母

周　佳，康亚妮^*

(上海交通大学系统生物医学研究院，系统生物医学教育部重点实验室，上海 200240)

摘　要：
摘　要：衰老是生物医学研究中的前沿与热点课题。酿酒酵母作为单细胞衰老研究的模式生物，为人体衰老机制的认识提供了重要线索，在生物医学研究中发挥了极为重要的作用。现以酿酒酵母作为细胞衰老研究的模式生物对相关研究及其分子调节机制进行简要综述。
关键词：单细胞；衰老；酿酒酵母；芽痕；非对称分裂

A model organism for cellular aging research: Saccharomyces cerevisiae

ZHOU Jia， KANG Ya-Ni^*

(Shanghai Center for Systems Biomedicine， Key Laboratory of Systems Biomedicine Ministry of Education， Shanghai Jiao Tong University， Shanghai 200240， China)

Abstract: Abstract: Aging is one of the forefront and hot topics in biomedical research. Saccharomyces cerevisiae has been normally used as a model organism for cellular aging research. It not only provides clues to understand the mechanisms of human aging， but also plays a vital role in biomedical research. Now we give a brief overview to the relevant research and its molecular regulation mechanism about S. cerevisiae as a biological model for cellular aging research.
Key words: single cell; aging; Saccharomyces cerevisiae; bud scars; asymmetric division