《生命科学》 2013, 25(4): 435-441
摘 要：摘 要：DNA 甲基化是真核生物表观遗传学重要的机制之一，在基因的表达调控中发挥着重要的作用。近年来，DNA 甲基化分析技术在动植物遗传育种领域中的应用研究已引起人们广泛关注。现从DNA 甲基化研究的重要性，DNA 甲基化检测的主要方法及DNA 甲基化与动植物种质资源鉴定、生长发育调控、杂种优势和胁迫的关系等方面，简要综述了国内外有关DNA 甲基化技术在动植物遗传育种实践中的应用研究进展，以期为动植物育种研究提供一条新的途径与思路。
关键词：DNA 甲基化；种质资源鉴定；基因表达调控；杂种优势分子机理
Abstract: Abstract: As one of the important epigenetic mechanisms in eukaryotes， DNA methylation plays a crucial role in regulation of gene expression. In recent years， more attention has been focused upon DNA methylation analysis in genetics and breeding programs of plants and animals. This paper reviewed the progress of research and applications of DNA methylation analysis in genetics and breeding of plants and animals， including the importance of DNA methylation in gene expression regulation， the detection methods of methylation， the relationship between DNA methylation and germplasm identification， regulation of growth and development， heterosis and stress， which can provide new approach and idea for plant and animal breeding.
Key words: DNA methylation; germplasm identification; gene expression regulation; molecular mechanism of heterosis
