《生命科学》 2013, 25(4): 388-395

组装抑制蛋白功能研究进展

叶忠峰，郭果为，刘　程，黄晓红^*

(福建师范大学生命科学学院，福建省发育与神经生物学重点实验室，福州 350108)

摘　要：摘　要：组装抑制蛋白(Profilin) 是最重要的肌动蛋白结合蛋白之一，它调控着单体肌动蛋白的聚合，并与其他细胞骨架蛋白相互作用。就Profilin 家族的结构特点、分布、功能及其动力学机制的研究进展作一简要综述，并指出目前在Profilin 家族动力学研究方面仍存在的不足以及需要更为深入的研究之处。
关键词：组装抑制蛋白；细胞骨架蛋白；动力学

Research proceeding of profilin and its functions

YE Zhong-Feng， GUO Guo-Wei， LIU Cheng， HUANG Xiao-Hong^*

(Fujian Key Laboratory of Developmental Biology and Neuroscience， College of Life Science， Fujian Normal University， Fuzhou 350108， China)

Abstract: Abstract: Profilin is one of the most important actin-binding proteins. It regulates actin polymerization and interacts with many cytoskeletal proteins. Herein， the structure characterizations， distributions and functions of the profilin family were reviewed， and the mechanisms in the regulation of actin dynamics were discussed. Finally， the deficiency in the research on the dynamics of profilin was pointed out.
Key words: profilin; cytoskeletal proteins; dynamics