《生命科学》 2013, 25(3): 289-294
摘 要:摘 要:Wnt5a 是一种具有代表性的非经典Wnt 蛋白,通过调控Wnt 信号途径而对细胞各方面的功能进行调节,如细胞的增殖、分化、迁移,肿瘤细胞的侵袭等。概述了Wnt5a 的受体、Wnt5a 介导的信号途径以及Wnt5a 在细胞运动中作用的最新研究进展。
Abstract: Abstract: Wnt5a is a representative noncanonical Wnt molecule, regulates a variety of cellular functions, such as proliferation, differentiation, migration, and so on. In this review, the new researches on its receptors, its influences on the pathways and cellular movement were overviewed.