《生命科学》 2012, 24(10): 1089-1097

抗冻蛋白特征、作用机理与预测新进展

李文轲， 马春森^*

(中国农业科学院植物保护研究所植物病虫害生物学国家重点实验室，北京 100193)

摘　要：

摘　要：抗冻蛋白(antifreeze proteins，AFPs)可以通过抑制冰晶生长保护生物体免受低温冻害，具有重要的生物学意义和应用价值。现在在鱼类、节肢动物、植物及微生物中均发现有AFPs的存在。基于对已有研究文献和相关网络数据的系统调查统计，详细描述了AFPs数据的类别特征，并对其作用机理的研究历史和最新取得的突破性进展作了较为系统的阐述，并对AFPs预测所取得的成果作了介绍，还对AFPs研究的现状和未来研究方向作了讨论和展望。

    

关键词：抗冻蛋白；抗冻机理；预测

    

中图分类号： Q51，Q71 文献标识码：A

Present properties， mechanism and prediction of antifreeze proteins

LI Wen-Ke， MA Chun-Sen^*

(State Key Laboratory for Biology of Plant Diseases and Insect Pests， Institute of Plant Protection， Chinese Academy of Agricultural Sciences， Beijing 100193， China)

Abstract:

Abstract: Antifreeze proteins (AFPs) protect the organism from freezing injury by preventing the growth of ice crystals. AFPs have great significance both in biology and application. So far， AFPs have been found in fishes， terrestrial arthropods， plants and microorganisms. Based on a systemic literature investigation and statistic analysis of AFPs data from the internet， we reviewed features of different types of AFPs， summarized the history and the latest remarkable progress about the research of AFPs mechanism. In addition， we presented current progress on the prediction of AFPs. At last， we prospected the future research direction of AFPs.

    

Key words: antifreeze proteins; antifreeze mechanism; prediction