《生命科学》 2012, 24(2): 161-168
摘 要:摘 要:硫化物是一种广泛分布的有毒物质。硫醌氧化还原酶是生物体硫化物代谢的一种关键酶。对该酶的发现与分布、序列特征、催化机制、催化特性、三维结构和生理功能等几个方面进行概述,并对该酶未来研究方向进行展望。
关键词:硫醌氧化还原酶;硫化物;序列特征;催化机制;三维结构
Abstract: Abstract: sulfide is a natural, widely distributed poisonous substance. Sulfide:quinone oxidoreductase (SQR) is a critical enzyme involving in organism sulfide metabolism. In this paper, we summarized recent progresses on SQR discovery and distribution, sequence characteristics, catalytic mechanism, three dimensional structure and its physiological function. Furthermore, we suggest some future research directions of SQR.
Key words: sulfide:quinone oxidoreductase; sulfide; sequence characteristics; catalytic mechanism; three dimensional structure