硫醌氧化还原酶研究进展
马玉彬1,2,史晓丽1,邵明瑜1,董英萍1,李金龙1,张志峰1*
(1 中国海洋大学海洋生物遗传育种教育部重点实验室,青岛 266003;2 中国科学院青岛生物能源与过程研究所生物燃料重点实验室,山东省能源生物遗传资源重点实验室,青岛 266101)

摘 要:摘 要:硫化物是一种广泛分布的有毒物质。硫醌氧化还原酶是生物体硫化物代谢的一种关键酶。对该酶的发现与分布、序列特征、催化机制、催化特性、三维结构和生理功能等几个方面进行概述,并对该酶未来研究方向进行展望。
关键词:硫醌氧化还原酶;硫化物;序列特征;催化机制;三维结构

Advances in research on sulfide: quinone oxidoreductase
MA Yu-Bin1,2, SHI Xiao-Li1, SHAO Ming-Yu1, DONG Ying-Ping1, LI Jin-Long1, ZHANG Zhi-Feng1*
(1 Key Laboratory of Marine Genetics and Breeding, Ocean University of China, Ministry of Education, Qingdao 266003, China; 2 Shandong Provincial Key Laboratory Of Energy Genetics, Key Laboratory of Biofuels, Qingdao Institute of
    Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, China)

Abstract: Abstract: sulfide is a natural, widely distributed poisonous substance. Sulfide:quinone oxidoreductase (SQR) is a critical enzyme involving in organism sulfide metabolism. In this paper, we summarized recent progresses on SQR discovery and distribution, sequence characteristics, catalytic mechanism, three dimensional structure and its physiological function. Furthermore, we suggest some future research directions of SQR.
Key words: sulfide:quinone oxidoreductase; sulfide; sequence characteristics; catalytic mechanism; three dimensional structure

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