糖类药物
杜晓光,耿美玉*
(中国科学院上海药物研究所,上海201203)

摘 要:

摘要:糖链作为重要的生物信息分子和高密度的信息载体,参与细胞生物几乎所有的生命过程,特别是在细胞分化、发育、免疫、老化、癌变、信息传递等生命基础活动和重大疾病过程中起着特异性的识别、介导与调控作用。由于糖类物质的多种多样的生物活性,糖类药物在抗肿瘤、老年痴呆、免疫、抗病毒等多个重大疾病领域广泛应用,而且其使用范围还在不断开拓中。因此,糖类药物生物活性多样,毒副作用低,具有广阔的发展前景。

    
关键词:糖类药物、生物活性、肿瘤、老年痴呆、抗病毒、免疫调节

    
中图分类号:Q53; R979.1  文献标志码:A

    

Carbohydrate drugs
DU Xiao-Guang, GENG Mei-Yu*
(Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China)

Abstract:

Abstract:As an important biological information molecules and high-density information carriers, sugar chain involved in almost all life processes in living beings, especially in cell differentiation, development, immunity, aging, cancer, signal transduction and other basic life activities and diseases. For the bioactivities of carbohydrates, carbohydrate drugs had been widely used in anti-tumor, Alzheimer{$39}s, immune, anti-virus, and other diseases. And the use of carbohydrates is still expanding. Therefore, the various bioactivities and low toxicity endow carbohydrates broad prospects.

    
Key words: carbohydrate drugs; biological activity; cancer; Alzheimer{$39}s; anti-virus; immune regulation

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