《生命科学》 2007, 19(1):

孢子体型自交不亲和反应臂重复蛋白ARC1

王茂广^1,2

1临沂师范学院生命科学学院，临沂 276005；2曲阜师范大学生命科学学院，曲阜 273165

摘　要：摘　要：臂重复蛋白ARC1(arm repeat containing 1, ARC1)是孢子体型自交不亲和信号传导途径下游非常重要的蛋白质因子，由臂重复结构域、U-box结构域、亮氨酸拉链/卷曲螺旋结构域、1个核定位信号和2个核输出信号组成，其中臂重复结构域和U-box结构域起主要功能。ARC1具有E3泛素连接酶活性，能够促进自交不亲和反应(self-incompatibility, SI )中的信号传导元件泛素化并降解。本文综述了ARC1蛋白的结构和功能，旨在阐明它在SI反应中的作用。
关键词：自交不亲和性；SRK；ARC1；泛素化

The arm repeat containing protein ARC1 in sporophytic self-incompatible response

WANG Maoguang^1,2

1 College of Life Science, Linyi Normal University, Linyi 276005, China; 2 College of Life Science, Qufu Normal University, Qufu 273165, China

Abstract: Abstract: ARC1(arm repeat containing 1 ) is a very important downstream protein factor in sporophytic self-incompatible signaling process. It is made up of arm repeat domain, U-box domain, leucine zipper domain/coiled-coil domain, one nuclear localization signal and two nuclear export signal, arm repeat domain and U-box domain are main functional domain. ARC1 has an E3 ubiquitin ligase activity and promotes the self-incompatible signaling process element ubiquitination and degradation. This article summarizes the structure and function of ARC1 protein to define its role in SI response.
Key words: self-incompatibility; SRK; ARC1; ubiquitination