《生命科学》 2010, 22(4): 345-351

WRKY转录因子功能的多样化

于延冲，乔　孟，刘振华，向凤宁^*

(山东大学生命科学学院植物细胞工程与种质创新教育部重点实验室，济南 250100)

摘　要：摘  要：WRKY是植物中一类重要的转录因子家族，其共同的特点是含有高度保守的核心氨基酸序列WRKYGQK，在C-末端有一个锌指结构。WRKY受到病原菌、损伤、SA(salicylic acid)等因子的诱导后表达，特异性识别(T)(T)TGAC(C/T)序列(W-box)，调节基因的表达而参与许多生理过程，如抗病、损伤、生长发育以及衰老等。该文主要介绍了WRKY的结构特点及其功能的研究进展。
关键词：WRKY；W-box；转录因子
中图分类号：Q943.2　　文献标识码：A

Diversification function of WRKY transcription factor

Yu Yan-chong， Qiao Meng， LIU Zhen-hua， Xiang Feng-ning^*

(Plant Cell Engineering and Germplasm Innovation Key Lab of Ministry of Education， Life Sciences School of Shandong University， Jinan 250100， China)

Abstract: Abstract: WRKY is a superfamily of transcription factors existing abroad in plants， containing a conserved WRKYGQK domain and having a zinc finger motif. The expression of WRKY is induced by pathogen， wounding， SA， etc. WRKY proteins regulate target genes?expression via binding the (T) (T) TGAC (C/T) sequence (W-box) located in their promoter regions. WRKY proteins involved in many physiological processes， such as resistance， wounding， development， senescence. In this article， we primarily interpret their structure and review the current progresses on their functions.
Key words: WRKY; W-box; transcription factor